This case study followed a 34-year-old man with PSC and ulcerative colitis who did not respond to multiple advanced therapies, and who had a liver transplant.

Before his liver transplant, he tried mesalamine and Remicade without achieving remission. After his liver transplant, his UC flared and he tried Remicade, Entyvio, Humira, Xeljanz, and Stelara. However, his CRP remained high and colonoscopies showed continuous inflammation.

His medical team was considering resection surgery, but then he started 500 mg OV twice daily and achieved clinical and endoscopic remission three months later.