In this 12-week pilot study, 35 adult PSC patients were randomized into one of 4 groups: 1. 125 mg oral vancomycin 4x/day 2. 250 mg oral vancomycin 4x/day 3. 250 mg metronizadole 3x/day 4. 500 mg metronizadole 3x/day One goal of this study was to investigate the safety and efficacy of these drugs. Another goal […]
A Triple Blinded, Randomized, Placebo-Controlled Clinical Trial to Evaluate the Efficacy and Safety of Oral Vancomycin in Primary Sclerosing Cholangitis: A Pilot Study
This 12-week study was a triple blinded, randomized, placebo-controlled trial performed on 29 patients in Iran. 11 patience were randomly assigned the placebo and 18 patients were treated with oral vancomycin (125 mg, four times a day) The vancomycin group showed a decrease in their alkaline phosphatase, sedimentation rate, GGT, and the Mayo Risk Score. […]