This paper is a collection of three brief case reports that describes the effect of oral vancomycin treatment in three patients with UC and PSC. All three patients achieved clinical remission and mucosal healing with vancomycin. The patients took 500 mg twice a day. Maintenance treatment with oral vancomycin led to sustained clinical and endoscopic […]
Open-Label Prospective Therapeutic Clinical Trials: Oral Vancomycin in Children and Adults with Primary Sclerosing Cholangitis
This research paper documents the impacts of oral vancomycin on the GGT, ALP, and ALT of 59 PSC patients. If patients weighed less than 30 kg, they took 50 mg vancomycin per kg each day. If patients weighed more than 30 kg, they took 500 mg vancomycin 3x each day. 96% experienced reduction of GGT, […]
Successful Response of Primary Sclerosing Cholangitis and Associated Ulcerative Colitis to Oral Vancomycin May Depend on Brand and Personalized Dose
This case report shares that a 23-year old female has been taking vancomycin for PSC for eight years, and achieved normalization of liver enzymes and resolution of UC symptoms with colonic mucosal healing. There has been no colon dysplasia, liver fibrosis or failure, bile duct stricture, or cancer. However, the patient experienced worsening symptoms when […]
Vancomycin for PSC Q&A with Dr. Davies: Presented by the Children’s PSC Foundation
In 2011, Dr. Yinka Davies, a pediatric gastroenterologist, held a teleconference call with the parents of children with PSC patients. The conversation was recorded into a written Q&A format. Topics cover: • Vancomycin safety, side effects, and vancomycin-resistant bacteria • The use of probiotics when taking vancomycin • The effect of vancomycin on other autoimmune […]
Oral Vancomycin as a Therapeutic Option for PSC: Presented by Dr. Yinka Davies
In this recording from the PSC Partners’ conference in 2018, Dr. Yinka Davies shares the promising research about vancomycin for PSC. She shares incredible case studies and discusses optimal vancomycin dosing regimens and the importance of brand and much more. Since vancomycin is not yet FDA-approved for PSC, Dr. James Tabibian had to discuss the […]