This 2024 case report discusses a patient with ulcerative colitis, PSC, and autoimmune hepatitis who responded well to oral vancomycin. This 30-year old woman went to the hospital with abdominal pain, bloody diarrhea, and vomiting bile. She tried multiple treatment regimens, but the only one that was effective was oral vancomycin. This insightful case report […]
Cancer Risk in Primary Sclerosing Cholangitis: Epidemiology, Prevention, and Surveillance Strategies
This research paper provides a helpful overview of the various types of cancers PSC patients are at risk of developing, as well as ways to screen for cancer. The cancers discussed in this paper are cholangiocarcinoma, gallbladder cancer, hepatocellular carcinoma, pancreatic cancer, and colorectal cancer. Screening methods covered in this paper include MRIs/MRCPs, CA 19-9 […]
Complete Biochemical Remission With Oral Vancomycin in a Patient With Primary Sclerosing Cholangitis and High Serum Immunoglobulin G4 Levels
This case study follows a 20-year old young man with ulcerative colitis and elevated AST, ALT, Alkaline Phosphatase, and IgG4, as well as narrowed bile ducts and liver inflammation and fibrosis. While steroids lowered his liver enzymes in the him short-term, they increased when he tapered off, so he was prescribed oral vancomycin (OV) at […]
“Living With PSC” Online Forum and Support Community
Countless stories have been shared and questions have been answered in this incredible online forum. This is a great place to find community and learn about others’ experiences with PSC, vancomycin, transplants, symptoms, and so much more.
Oral Vancomycin Therapy in a Child with Primary Sclerosing Cholangitis and Severe Ulcerative Colitis
This case study reports on a 15 year old girl with PSC and ulcerative colitis. After taking oral vancomycin, the girl achieved normalization of her liver numbers and bile ducts, resolution of UC symptoms, and colonic mucosal healing. The investigators believe the vancomycin may be acting both as an antibiotic (by altering the intestinal microbiome) […]
Oral Vancomycin Induces Sustained Deep Remission in Adult Patients with Ulcerative Colitis and Primary Sclerosing Cholangitis
This paper is a collection of three brief case reports that describes the effect of oral vancomycin treatment in three patients with UC and PSC. All three patients achieved clinical remission and mucosal healing with vancomycin. The patients took 500 mg twice a day. Maintenance treatment with oral vancomycin led to sustained clinical and endoscopic […]