This retrospective study looked at 22 adult patients who had confirmed PSC and IBD and who had been on oral vancomycin for a period of time. 15 of the 22 patients (68.2%) had less therapy intensification on oral vancomycin therapy compared to off oral vancomycin therapy. There were also less steroid prescriptions for those taking […]
Coexisting Primary Sclerosing Cholangitis and Autoimmune Hepatitis: Overlapping Challenges in Diagnosis and Treatment
This 2024 case report discusses a patient with ulcerative colitis, PSC, and autoimmune hepatitis who responded well to oral vancomycin. This 30-year old woman went to the hospital with abdominal pain, bloody diarrhea, and vomiting bile. She tried multiple treatment regimens, but the only one that was effective was oral vancomycin. This insightful case report […]
Oral Vancomycin Induces, Maintains Remission of UC in Patients with UC-PSC
This article shares the insights of a study presented at Digestive Disease Week in 2019. This retrospective chart review is “the largest case study to date to examine oral vancomycin in patients with UC-PSC.” This research showed that “oral vancomycin safely induced and maintained remission of ulcerative colitis among a subset of patients with ulcerative […]
Ulcerative Colitis Pipeline Insight 2024 | FDA Approvals, Clinical Trials, and Therapies
This press release shares data gathered by DelveInsight—a healthcare-focused market research and consulting firm. This article is super exciting and hopeful, as it shows some promising IBD therapies in the pipeline, from pills to subcutaneous injections to IV biologics. One of the therapies listed under “promising ulcerative colitis therapies” is oral vancomycin! I believe there’s […]
Dr. Ken Cox Presentation with Cincinnati Children’s Hospital: Treatment of Pediatric PSC with Oral Vancomycin
In this presentation, Dr. Ken Cox—the doctor who discovered the use of oral vancomycin for PSC—shares an enlightening presentation on this matter. Topics included are: • Dr. Cox’s experience treating children with PSC with oral vancomycin • Possible mechanisms in which oral vancomycin treats PSC • Long-term treatment of oral vancomycin • Effect of oral […]
Microbiome Responses to Vancomycin Treatment in a Child With Primary Sclerosing Cholangitis and Ulcerative Colitis
This case report shares the positive changes in the microbiome after a nine-year-old by took vancomycin for 90 days. Thanks to vancomycin, his ulcerative colitis symptoms resolved, his fecal calprotectin normalized, and his GGT (a liver function test that helps monitor PSC) declined and returned to normal levels!